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When Does Jaundice Peak in Newborns?

by Jessica

Jaundice is a common condition in newborns, characterized by a yellowing of the skin and the whites of the eyes. This yellowing occurs due to a high level of bilirubin in the blood. Bilirubin is a yellow pigment produced during the normal breakdown of red blood cells. While jaundice is often harmless, it is important to monitor and manage it to prevent any potential complications.

Understanding Newborn Jaundice

What Causes Jaundice in Newborns?

Jaundice in newborns is primarily caused by the immaturity of the liver. In newborns, the liver is still developing and may not be efficient in processing bilirubin. This leads to an accumulation of bilirubin in the blood, causing the characteristic yellowing. Additionally, newborns have a higher turnover of red blood cells, which contributes to an increased production of bilirubin.

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There are several types of jaundice that can affect newborns:

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Physiological Jaundice: This is the most common type of jaundice and usually appears between the second and fourth day after birth. It is considered a normal part of a newborn’s adjustment to life outside the womb and usually resolves on its own.

Breastfeeding Jaundice: This type of jaundice can occur in breastfed babies due to inadequate intake of breast milk, leading to dehydration and decreased elimination of bilirubin.

Breast Milk Jaundice: This is a rare type of jaundice that occurs in some breastfed babies after the first week of life. It is thought to be caused by substances in the breast milk that increase the reabsorption of bilirubin from the intestines.

Hemolytic Jaundice: This occurs when there is an excessive breakdown of red blood cells, which can be due to blood group incompatibility between the mother and baby, or certain inherited conditions like G6PD deficiency.

When Does Jaundice Peak?

The Peak of Physiological Jaundice

Physiological jaundice typically peaks between the third and fifth day of life. During this time, bilirubin levels are at their highest as the baby’s liver is still developing the ability to process and eliminate bilirubin efficiently. In most cases, the bilirubin levels gradually decrease after this peak as the liver matures and the baby begins to excrete bilirubin through urine and stool.

Breastfeeding and Breast Milk Jaundice Peaks

Breastfeeding jaundice usually peaks around the third to fifth day of life, similar to physiological jaundice. This is because, in the early days, some newborns may not get enough breast milk, which can lead to dehydration and reduced bilirubin elimination. As breastfeeding becomes established and the baby starts receiving adequate milk, bilirubin levels typically begin to decrease.

Breast milk jaundice, on the other hand, may peak later, typically during the second or third week of life. In some cases, it can persist for several weeks but usually resolves without the need for treatment.

Hemolytic Jaundice Peaks

Hemolytic jaundice often peaks earlier, within the first 24 hours of life. This type of jaundice can be more severe and may require immediate medical attention. The early peak is due to the rapid breakdown of red blood cells, leading to a swift increase in bilirubin levels.

Signs and Symptoms of Jaundice

Recognizing the signs of jaundice in newborns is crucial for timely intervention. The most common signs include:

Yellowing of the skin and whites of the eyes, starting from the face and progressing down the body.

Poor feeding or difficulty breastfeeding.

Lethargy or excessive sleepiness.

Dark urine (newborn urine is usually colorless).

Pale-colored stool (normal stool is yellow or orange).

Parents should regularly observe their baby’s skin color, especially in natural light, and report any changes to a healthcare provider.

Diagnosing Jaundice

Jaundice is often diagnosed based on a physical examination. However, to determine the severity of jaundice, healthcare providers may use a bilirubin meter, which measures the amount of bilirubin in the skin. In some cases, a blood test may be required to measure the exact level of bilirubin in the blood.

Monitoring Bilirubin Levels

Monitoring bilirubin levels is important to ensure that they do not reach a dangerous level. The timing of bilirubin level checks is critical:

Within the first 24 hours: Babies at risk of hemolytic jaundice should have their bilirubin levels checked within the first 24 hours after birth.

Between 24 to 48 hours: This is the typical time frame for checking bilirubin levels in all newborns, especially those with signs of jaundice.

After 48 hours: If bilirubin levels are high, additional tests may be done to monitor the trend and determine if treatment is necessary.

SEE ALSO: Can Jaundice Come and Go in Newborns?

Treatment of Newborn Jaundice

The treatment of jaundice depends on the severity of the condition. In many cases, no treatment is needed, and the jaundice resolves on its own. However, if bilirubin levels are high or rising, treatment options may include:

Phototherapy

Phototherapy is the most common treatment for jaundice in newborns. It involves placing the baby under special lights that help break down bilirubin in the skin. This treatment is effective and safe, with minimal side effects. Phototherapy can be done in the hospital or at home, depending on the severity of jaundice and the healthcare provider’s recommendation.

Exchange Transfusion

In severe cases of jaundice, where bilirubin levels are dangerously high, an exchange transfusion may be required. This procedure involves removing small amounts of the baby’s blood and replacing it with donor blood. Exchange transfusion rapidly reduces bilirubin levels and is usually reserved for babies who do not respond to other treatments.

Increasing Feedings

For breastfeeding jaundice, increasing the frequency of feedings can help lower bilirubin levels by promoting more frequent bowel movements, which help eliminate bilirubin from the body. In some cases, healthcare providers may recommend supplementing with formula if the baby is not getting enough breast milk.

Preventing Jaundice in Newborns

While not all cases of jaundice can be prevented, there are steps that can be taken to reduce the risk:

Early and Frequent Feeding: Ensuring that the baby is fed early and often helps promote regular bowel movements, which aids in the elimination of bilirubin.

Monitoring for Jaundice: Parents should be vigilant in observing their baby for signs of jaundice, especially in the first few days after birth.

Regular Check-ups: Attending regular check-ups with a pediatrician allows for early detection and management of jaundice.

When to Seek Medical Attention

Parents should seek medical attention if they notice any of the following:

The baby’s jaundice is worsening or spreading.

The baby is feeding poorly or has difficulty waking up for feedings.

The baby’s urine is dark or their stool is pale.

The baby seems excessively sleepy or lethargic.

Early intervention can prevent complications such as kernicterus, a rare but serious condition that can result from extremely high bilirubin levels.

Complications of Untreated Jaundice

If left untreated, severe jaundice can lead to serious complications, including:

Kernicterus: This is a form of brain damage that can occur when very high levels of bilirubin cross into the brain tissue. Kernicterus can cause permanent neurological damage, including hearing loss, vision problems, and intellectual disabilities.

Acute Bilirubin Encephalopathy: This is a temporary condition that occurs when high bilirubin levels affect the brain. Symptoms include lethargy, poor feeding, and a high-pitched cry. Prompt treatment can prevent permanent damage.

Long-term Outlook for Babies with Jaundice

The majority of babies with jaundice recover fully without any long-term effects. With proper monitoring and treatment, the risk of complications is low. Parents should follow their healthcare provider’s recommendations for follow-up care to ensure their baby’s bilirubin levels have returned to normal.

Conclusion

Jaundice is a common condition in newborns, with physiological jaundice typically peaking between the third and fifth day of life. While most cases are mild and resolve on their own, it is important to monitor jaundice closely to prevent complications. Understanding the causes, signs, and treatment options for jaundice can help parents and caregivers manage this condition effectively and ensure the well-being of their newborns.

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